教育与工作经历

2004.09-2006.07    曲阜师范大学   学士    化学

2006.09-2011.10    湖南大学       博士    分析化学

2011.11-至今         曲阜师范大学   教授

2006年9月-2011年10月，在湖南大学化学生物传感与计量学国家重点实验室攻读博士学位（硕博连读），师从俞汝勤院士、张晓兵教授，在博士研究后期得到了谭蔚泓教授的指导。主要从事基于功能核酸和纳米材料的生物传感器的研究及应用。已在包括Journal of the American Chemical Society、Analytical Chemistry、Small、Chemical Communications、Biosensors and Bioelectronics等权威SCI源刊物上发表国际学术论文十几篇。2011年10月获湖南大学分析化学专业理学博士学位后任职于曲阜师范大学化学化工学院，山东省生命有机分析重点实验室。

科研项目

1. 主持国家自然科学基金青年项目1项：新型 DNAzyme 荧光纳米探针的构建及其生物医学应用研究（21205068）

2. 主持博士基金项目1项：基于银纳米簇信标构建非标记DNAzyme工具探针用于非辅助因子目标物的检测研究（BS2013SW012）

3. 主持化学生物传感与计量学国家重点实验室开放基金1项：基于DNAzyme 自组装纳米材料荧光探针的构建及初步生物医学应用研究（2013011）

获奖情况

山东软科学优秀成果奖一等奖：以生物传感技术构建疾病早期筛查机制的调查分析研究（山东软科学优秀成果奖励委员会）第二位

发表论文

[1]           Rong-Mei Kong, Xiao-Bing Zhang*, Liang-Liang Zhang, Yan Huang, Dan-Qing Lu, Weihong Tan*, Guo-Li Shen, and Ru-Qin Yu. Molecular Beacon-Based Junction Probes for Efficient Detection of Nucleic Acids via a True Target-Triggered Enzymatic Recycling Amplification. Analytical Chemistry, 2011, 83(1), 14-17.（SCI一区，IF=5.856）

[2]           Rong-Mei Kong, Xiao-Bing Zhang*, Zhuo Chen, Hong-Min Meng, Zhi-Ling Song, Weihong Tan*, Guo-Li Shen, Ru-Qin Yu. A Unimolecular Catalytic DNA Biosensor for Amplified Detection of L-Histidine via an Enzymatic Recycling Cleavage Strategy. Analytical Chemistry, 2011, 83(20), 7603-7607. （SCI一区，IF=5.856）

[3]           Rong-Mei Kong, Xiao-Bing Zhang*, Liang-Liang Zhang, Xiao-Yong Jin, Shuang-Yan Huan, Guo-Li Shen and Ru-Qin Yu*. An Ultrasensitive Electrochemical “Turn-On” Label-Free Biosensor for Hg²⁺ with AuNP-Functionalized Reporter DNA as a Signal Amplifier. Chemical Communications, 2009, 5633-5635. （SCI二区，IF=6.169）

[4]           Rong-Mei Kong, Xiao-Bing Zhang*, Zhuo Chen, Weihong Tan*. Aptamer-assembled Nanomaterials for Biosensing and Biomedical Applications. Small, 2011, 7(17), 2428-2436.（SCI二区，IF=8.349）

[5]           Rong-Mei Kong, Ting Fu, Ni-Na Sun, Feng-Li Qu, Shu-Fang Zhang, Xiao-Bing Zhang. Pyrophosphate-regulated Zn²⁺-dependent DNAzyme activity: An amplifiedfl uorescence sensing strategy for alkaline phosphatase. Biosensors and Bioelectronics, 2013, 50, 351- 355. (SCI 一区，IF=6.451)

[6]           Rong-Mei Kong, Zhi-Ling Song, Hong-Min Meng, Xiao-Bing Zhang, Guo-Li Shen, Ru-Qin Yu. A label-free electrochemical biosensor for highly sensitive and selective detection of DNA via a dual-amplified strategy. Biosensors and Bioelectronics, 2014, 54, 442- 447. (SCI 一区，IF=6.451)

[7]           Rong-Mei Kong, Zhuo Chen, Xiao-Bing Zhang*, Weihong Tan*. Cell-SELEX-based Aptamer-Conjugated Nanomaterials for Enhanced Targeting of Cancer Cells. Science in China Series B: Chemistry, 2011, 54(8), 1218-1226. （SCI 四区，IF=1.02）

[8]           Xiao-Bing Zhang*, Rong-Mei Kong, Yi Lu*. Metal Ion Sensors Based on DNAzymes and Related DNA Molecules. Annual Review of Analytical Chemistry, 2011, 4, 105-128.（SCI一区，IF=11.806）

[9]           Li-Min Lu, Xiao-Bing Zhang*, Rong-Mei Kong, Bin Yang, Weihong Tan*. A Ligation-triggered DNAzyme Cascade for Amplified Fluorescence Detection of Biological Small Molecules with Zero-Background Signal. Journal of the American Chemical Society, 2011, 133 (30), 11686-11691.（SCI一区，IF=9.907）

[10]       Xu-Hua Zhao, Rong-Mei Kong, Xiao-Bing Zhang*, Hong-Min Meng, Wei-Na Liu, Weihong Tan*, Guo-Li Shen, and Ru-Qin Yu. Graphene–DNAzyme Based Biosensor for Amplified Fluorescence “Turn-On” Detection of Pb²⁺ with a High Selectivity. Analytical Chemistry, 2011, 83(13), 5062-5066. （SCI一区，IF=5.856）

[11]       Yun-Hong Sun, Rong-Mei Kong, Dan-Qing Lu, Xiao-Bing Zhang*, Hong-Min Meng, Weihong Tan*, Guo-Li Shen and Ru-Qin Yu. A Nanoscale DNA–Au Dendrimer as a Signal Amplifier for the Universal Design of Functional DNA-Based SERS Biosensors. Chemical Communications, 2011, 47(13), 3840-3842.（SCI二区，IF=6.169）

[12]       Kejun Feng, Rongmei Kong, Hua Wang, Shufang Zhang, Fengli Qu*. A universal amplified strategy for aptasensors: Enhancing sensitivity through allostery-triggered enzymatic recycling amplification. Biosensors and Bioelectronics, 2012, 38, 121-125. （SCI一区，IF=5.602）

[13]       Rong Hu, Xiao-Bing Zhang*, Rong-Mei Kong, Xu-Hua Zhao, Jianhui Jiang*, Weihong Tan*. Nucleic Acid–Functionalized Nanomaterials for Bioimaging Applications. Journal of Materials Chemistry, 2011, 21, 16323-16334. （SCI二区，IF=5.968）

[14]       Rong Hu, Ting Fu, Xiao-Bing Zhang*, Rong-Mei Kong, Li-Ping Qiu, Ya-Ru Liu, Xiao-Tong Liang, Weihong Tan*, Guo-Li Shen, and Ru-Qin Yu. Proximity-Dependent Surface Hybridization Strategy for Constructing Efficient Signal-On Electrochemical DNAzyme Sensing System. Chemical Communications, 2012, 48, 9507-9509.（SCI二区，IF=6.169）

[15]       Rong Hu, Ya-Ru Liu, Rong-Mei Kong, Michael J. Donovan, Xiao-Bing Zhang*, Weihong Tana, Guo-Li Shen, Ru-Qin Yu*. Double-strand DNA-templated Formation of Copper Nanoparticles as Fluorescent Probe for Label Free Nuclease Enzyme Detection. Biosensors and Bioelectronics, 2013, 42, 31-35.（SCI一区，IF=6.451）

[16]       Lu Ding, Jinmao You, Rongmei Kong, Fengli Qu∗, Signal amplification strategy for sensitive immunoassay of prostatespecific antigen (PSA) based on ferrocene incorporated polystyrenespheres. Analytica Chimica Acta, 2013, 793, 19-25. (SCI二区，IF=4.718)

[17]       Ting Fu, Xu-Hua Zhao, Hua-Rong Bai, Zi-Long Zhao, Rong Hu, Rong-Mei Kong, Xiao-Bing Zhang,* Weihong Tan* and Ru-Qin Yu. A superquenched DNAzyme–perylene complex: a convenient, universal and low-background strategy for fluorescence catalytic biosensors. Chemical Communications, 2013, 49, 6644-6646. (SCI二区，IF=6.718）

[18]       Zhi-Xiang Han, Hong-Yuan Luo, Xiao-Bing Zhang*, Rong-Mei Kong, Guo-Li Shen, Ru-Qin Yu*. A Ratiometric Chemosensor for Fluorescent Determination of Hg²⁺ Based on a New Porphyrin-Quinoline Dyad. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2009, 72(5), 1084-1088. （SCI 四区，IF=1.511）

[19]       Shufang Zhang, Xuejun Sun, Fengli Qu, Rongmei Kong. Molecular spectroscopic studies on the interaction of ferulic acid with calf thymus DNA. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2013, 112, 78–83.（SCI 三区，IF=2.129）