魏伟博士简介:1982.09出生,山东滕州人。教授,硕士生导师,中科院成都生物研究所药物化学博士,加拿大麦吉尔大学(McGill University)博士后(合作导师 Chao-Jun Li),山东省优秀青年人才基金获得者(省优青), 山东省高校“青创科技计划”绿色化学团队学术带头人,入选曲阜师范大学“1361”人才工程第二层次。担任Chin. Chem. Lett; Chin J. Org. Chem青年编委。
科研方面: 近年来一直致力于有机合成化学和药物化学方面的研究工作,目前发表SCI论文100余篇,其中在Angew. Chem. Int. Ed, Chemical Science, Green Chemistry, Chem Commun, Organic Letters, Journal of Organic Chemistry等国际知名学术杂志上发表第一或通讯作者SCI论文66余篇(SCI二区(IF>4)以上论文40篇,其中IF>10论文7篇),总引用4000余次。H-index因子38。6篇代表性论文是2021年全球本学科ESI前1%高被引top论文。2017年获山东省高等学校科学技术奖一等奖(首位)《具有抗癌等重要生物活性有机医药材料的绿色构筑研究》;2019年获得山东省自然科学奖二等奖(第二位)《具有抗肿瘤等生物活性药物中间体的绿色构建》,2020年获山东省高等学校科学技术奖二等奖(首位)《含硫医药材料的绿色构建》,申请国家发明专利12项,授权9项。 教学情况: 获得全国微课教学比赛三等奖,山东省微课教学比赛一等奖,主讲《有机化学》,《有机化学实验》,《中级有机化学实验》等课程;主持完成曲阜师范大学精品实验 1 项,指导国家级大学生创新创业项目 2 项,指导本科生在 2017和 2018 连续两年获得山东省优秀学士毕业论文。指导研究生获得2021年山东省优秀硕士毕业论文。 药物研发方面: 2008-2012年 成都地奥集团药物研究所 药物研发实习研究员。参与完成抗癌药物卡陪他滨合成路线设计、工艺研究、中试放大和制剂等方面的研究。参与完成牛磺熊去氧胆酸的合成路线设计、工艺研究、中试放大方面的研究。
代表性奖励情况:
2013 年获全国高校微课教学比赛三等奖(个人); 2013 年获山东省高校微课教学比赛一等奖(个人), 2014 年获山东省高等学校优秀科研成果奖三等奖(首位); 2014 年获山东省自然科学学术创新二等奖(首位); 2015 年获山东省高等学校优秀科研成果奖三等奖(第二位); 2017 年获山东省高等学校优秀科研成果奖一等奖(首位) 2017 年获得山东省优秀学士毕业论文指导老师(个人); 2017 年获曲阜师范大学优秀研究生指导老师(个人)。 2017 年获曲阜师范大学教学建设成果奖二等奖(首位) 2017 年获山东省高等学校优秀科研成果奖三等奖(第二位) 2018 年被评为曲阜师范大学“先进科研工作者”(个人) 2018 年获曲阜师范大学优秀研究生指导老师(个人) 2018 年获山东省优秀学士毕业论文指导老师(个人) 2019 年获曲阜师范大学优秀研究生指导老师(个人) 2019 年获山东省自然科学奖二等奖(第二位) 2020 年获曲阜师范大学优秀硕士毕业论文指导老师(个人) 2020 年获曲阜师范大学优秀研究生指导老师(个人) 2020年山东省高等学校优秀科研成果奖二等奖(首位) 2021年获山东省优秀学硕士毕业论文指导老师(个人)
研究生、本科生招生与培养情况:
已毕业研究生5名,分别获得获国家奖学金3人,研究生圣地英才奖5人,其中3人被天津大学、中国人民大学录取为博士研究生。在读研究4名,多人次获得曲阜师范大学优秀研究生、一等/二等学业奖学金、研究生单项奖等。 每年招收2名有机化学和材料化工专业的研究生,欢迎对有机合成、药物合成感兴趣的同学加入本实验室攻读硕士学位!!并每年招收3-5名本科毕业论文、5-6名优秀的大二/大三本科生进行科研训练,多名本科毕业同学以优异成绩被中科院、985/211高校录取,欢迎优秀的本科生加盟!
联系方式: 办公室:实验中心B区306. E-mail: weiweiqfnu@163.com QQ: 471068894
代表性论文:
[1] Qishun Liu,# Leilei Wang,# Huilan Yue, Jiang-Sheng Li, Zidan Luo and Wei Wei,* Catalyst-free visible-light-initiated oxidative coupling of aryldiazo sulfones with thiols leading to unsymmetrical sulfoxides in air, Green Chem. 2019, 21, 1609–1613.SCI 一区IF=10.182 [2] Yufen Lv,# Pengli Bao,# Huilan Yue,* Jiang-Sheng Li and Wei Wei,* Visible-light-mediated metal-fe decarboxylative acylations of isocyanides with α-oxocarboxylic acids and water leading to α-ketoamides, Green Chem. 2019, 21, 6051–6055. SCI 一区IF=10.182 [3] Wei Wei,* Huanhuan Cui, Huilan Yue* and Daoshan Yang*, Visible-light-enabled oxyazidation of alkenes leading to α-azidoketones in air. Green Chem. 2018, 20, 3197–3202. SCI 一区IF=10.182 [4] Wei Wei,* Huanhuan Cui, Daoshan Yang, Huilan Yue, Chenglong He, Yulong Zhang, Hua Wang,* Visible-light-enabled spirocyclization of alkynes leading to 3-sulfonyland 3-sulfenyl azaspiro[4,5]trienones, Green Chem. 2017, 19, 5608–5613.SCI 一区IF=10.182 [5] Huanhuan Cui, Wei Wei,* Daoshan Yang, Yulong Zhang, Huijuan Zhao, Leilei Wang and Hua Wang*,Visible-light-induced selective synthesis of sulfoxides from alkenes and thiols using air as the oxidant. Green Chem, 2017, 19, 3520-3524.SCI 一区IF=10.182 [6] Wei Wei, Xi-Jie Dai, Haining Wang, Chenchen Li, Xiaobo Yang and Chao-Jun Li*, Ruthenium(II)-catalyzed olefination via carbonyl reductive cross-coupling, Chemical Science, 2017, 8, 8193-8197. SCI 一区 IF=9.346 [7] Pengli Bao, Fei Liu, Yufen Lv, Huilan Yue,* Jiang-Sheng Li and Wei Wei,* Visible-light-promoted acridine red catalyzed aerobic oxidative decarboxylative acylation of α-oxo-carboxylic acids with quinoxalin-2(1H)-ones, Org. Chem. Front. 2020, 7, 492–498. SCI 一区IF=5.155 [8] Ruisheng Liu, Qishun Liu, Haoran Meng, Hongyu Ding, Jindong Hao,Zhongyin Ji, Huilan Yue * and Wei Wei*,Metal-free visible-light-induced aerobic oxidation of α-diazoesters leading to α-ketoesters in air, Org. Chem. Front., 2021, 8, 1970. SCI 一区IF=5.155 [9] Wenjing Bai, Jianxin Ji , Qiang Huang , Wei Wei*, Synthesis and evaluation of new thiourea derivatives as antitumor and antiangiogenic agents, Tetrahedron Letters 61 (2020) 152366 [10] Na Meng, Leilei Wang, Qishun Liu, Qinyu Li, Yufen Lv,* Huilan Yue,* Xiaojuan Wang, and Wei Wei*,Metal-Free Trifluoroalkylation of Quinoxalin-2(1H)‑ones with Unactivated Alkenes and Langlois’ Reagent,J. Org. Chem. 2020, 85, 6888−6896 SCI 二区topIF=4.83 [11] Yufen Lv, Huanhuan Cui, Na Meng, Huilan Yue*, Wei Wei,* Recent advances in the application of sulfinic acids for the construction of sulfur-containing compounds, Chin. Chem. Lett. 2021, https://doi.org/10.1016/j.cclet.2021.06.068,SCI 二区IF=6.779 [12] Zhiwei Wang, Qishun Liu, Ruisheng Liu, Zhongyin Ji, Yan Li, Xiaohui Zhao, Wei Wei,* Visible-light-initiated 4CzIPN catalyzed multi-component tandem reactions to assemble sulfonated quinoxalin-2(1H)-ones, Chin. Chem. Lett. 2021, https://doi.org/10.1016/j.cclet.2021.08.036,SCI 二区IF=6.779 [13] Na Meng; Yufen Lv; Qishun Liu; Ruisheng Liu; Xiaohui Zhao*; Wei Wei*,Visible-light-induced three-component reaction of quinoxalin-2(1H)-ones, alkenes and CF3SO2Na leading to 3-trifluoroalkylated quinoxalin-2(1H)-ones, Chin. Chem. Lett. 2021, 32, 258-262,SCI 二区IF=6.779 [14] Qishun Liu , Yufen Lv, Ruisheng Liu, Xiaohui Zhao*, Jiawen Wang, Wei Wei*, Chin. Chem. Lett. 2021, 32, 136-139 SCI 二区IF=6.779 [15] Leilei Wang, Min Zhang, Yulong Zhang, Qishun Liu, Xiaohui Zhao*, Jiang-Sheng Li, Zidan Luo, Wei Wei,* Metal-free visible-light-induced oxidative cyclization reaction of 1,6-enynes and arylsulfinic acids leading to sulfonylated benzofurans, Chin. Chem. Lett. 2020, 31, 67–70. SCI 二区IF=6.779 [16] Qiang Huang, Lei Zhu, Dong Yi*, Xiaohui Zhaoc*, and Wei Wei,* Silver-mediated aminophosphinoylation of propargyl alcohols witharomatic amines and H-phosphine oxides leading to α-aminophosphine oxides, Chin. Chem. Lett. 2020, 31, 373–376. SCI 二区IF=6.779 [17] Qishun Liu, Fei Liu, Huilan Yue, Xiaohui Zhao,* Jiangsheng Li, and Wei Wei,* Photocatalyst-Free Visible Light-Induced Synthesis of β-OxoSulfones via Oxysulfonylation of Alkenes with Arylazo Sulfones and Dioxygen in Air, Adv. Synth. Catal. 2019, 361, 5277–5282 SCI 一区IF=5.48 [18] Pengli Bao, Huilan Yue, Na Meng, Xiaohui Zhao,* Jiangsheng Li, and Wei Wei,* Copper-Catalyzed Three-Component Reaction of Alkynes, TMSN3, and Ethers: Regiocontrollable Synthesis of N1 - and N2‑Oxyalkylated 1,2,3-Triazoles, Org. Lett. 2019, 21, 7218−7222.SCI 一区IF=6.03 [19] Qiang Huang, Kaikai Dong, Wenjing Bai, Dong Yi, Jian-Xin Ji,* and Wei Wei,* TEMPO-Catalyzed Aminophosphinoylation of Ethers via Tandem C(sp3)−H and C(sp3)−O Bond Cleavage, Org. Lett. 2019, 21, 3332−3336.SCI 一区IF=6.03 [20] Pengli Bao, Leilei Wang, Huilan Yue, Yun Shao, Jiangwei Wen, Daoshan Yang, Xiaohui Zhao, Hua Wang, and Wei Wei,* Metal-Free Catalytic Synthesis of Thiocarbamates Using Sodium Sulfinates as the Sulfur Source, J. Org. Chem. 2019, 84, 2976−2983. SCI 二区top [21] Pengli Bao, Na Meng, Yufen Lv, Huilan Yue, Jiang-Sheng Li and Wei Wei,* Selective assembly of N1- and N2-alkylated 1,2,3- triazoles via copper-catalyzed decarboxylative cycloaddition of alkynyl carboxylic acids with ethers and azidotrimethylsilane, Org. Chem. Front. 2019, 6, 3983–3988.SCI 一区IF=5.155 [22] Wei Wei,* Pengli Bao, Huilan Yue,* Sitong Liu, Leilei Wang, Yudong Li, and Daoshan Yang, Visible-Light-Enabled Construction of Thiocarbamates from Isocyanides, Thiols, and Water at Room Temperature, Org. Lett. 2018, 20, 5291−5295.SCI 一区IF=6.03 [23] Wei Wei,* Leilei Wang, Pengli Bao, Yun Shao, Huilan Yue, Daoshan Yang, Xiaobo Yang, Xiaohui Zhao,* and Hua Wang, Metal-Free C(sp2)−H/N−H Cross-Dehydrogenative Coupling of Quinoxalinones with Aliphatic Amines under Visible-Light Photoredox Catalysis, Org. Lett. 2018, 20, 7125−7130.SCI 一区IF=6.03 [24] Wei Wei,* Leilei Wang, Huilan Yue,* Pengli Bao, Weiwei Liu, Changsong Hu, Daoshan Yang, and Hua Wang, Metal-Free Visible-Light-Induced C−H/C−H Cross-Dehydrogenative Coupling of Quinoxalin-2(H)-ones with Simple Ethers, ACS Sustainable Chem. Eng. 2018, 6, 17252−17257.SCI 一区IF=7.632 [25] Wei Wei,* Huanhuan Cui, Huilan Yue* and Daoshan Yang*, Visible-light-enabled oxyazidation of alkenes leading to α-azidoketones in air. Green Chem. 2018, 20, 3197–3202. SCI 一区IF=9.480 [26] Daoshan Yang, * Guoqing Li, Chengyu Xing, Wenwen Cui, Kexin Li and Wei Wei*, Metal- and photocatalyst-free visible-lightpromoted regioselective selenylation of coumarin derivatives via oxidation-induced C-H functionalization, Org. Chem. Front. 2018, 5, 2974-2979.SCI 一区IF=5.155 [27] Leilei Wang,# Huilan Yue,# Daoshan Yang, Huanhuan Cui, Minghui Zhu, Jinming Wang, Wei Wei,* Hua Wang*, Metal-free Oxidative Coupling of Aromatic alkenes with Thiols Leading to (E)-Vinyl sulfones. J. Org. Chem., 2017, 82, 6857-6864. SCI 二区topIF=9.480 [28] Wei Wei*, Huanhuan Cui, Daoshan Yang, Xiaoxia Liu, Chenglong He, Shicui Dai, Hua Wang*. Metal-free molecular iodine catalyzed direct sulfonylation of pyrazolones with sodium sulfinates leading to sulfonated pyrazoles at room temperature, Org. Chem. Front. 2017, 4, 26-30.SCI 一区IF=5.155 [29] Qiang Fu, Dong Yi, Zhijie Zhang, Wu Liang, Suyuan Chen, Lu Yang, Qiang Zhang,* Jianxin Ji and Wei Wei*, Copper-catalyzed aerobic oxidative coupling of ketones with P(O)–H compounds leading to β-ketophosphine oxides, Org. Chem. Front. 2017, 4, 1385-1389.SCI 一区IF=5.155 [30] Huanhuan Cui, Xiaoxia Liu, Wei Wei*, Daoshan Yang, Chenglong He, Tiantian Zhang, and Hua Wang*, Molecular iodine Mediated Difunctionalization of Alkenes with Nitriles and Thiols Leading to β-Acetamido Sulfides, J. Org. Chem. 2016, 81, 2252−2260 SCI 二区top IF=4.812 |