![](/__local/1/59/D9/17CC7081379FC0635BB7465C789_C16AE0B7_21EC.jpg)
闫克鲁(博士、副教授、硕士生导师)
研究领域:过渡金属催化C–H键活化、光催化合成方法学研究
招生专业:有机化学、化学工程
Email:yankl@qfnu.edu.cn;QQ: 939143215
实验室:实验中心B612;办公室:实验中心B603
学习及工作经历
2008.9-2012.6,齐鲁工业大学,药物制剂,学士
2013.9-2016.6,曲阜师范大学,有机化学,硕士,导师:王桦教授、杨道山教授
2016.9-2019.6,南开大学,有机化学,博士,导师:王佰全教授
2019.7-2021.12,曲阜师范大学,化学与化工学院,制药工程教研室,讲师
2022.1至今,曲阜师范大学,化学与化工学院,制药工程教研室,副教授
2019.9至今,曲阜师范大学,化学与化工学院,制药工程教研室主任
主讲课程
《生物化学》、《杂环化学》、《制药工程仿真实验》、《有机化学实验》
科研项目
(1)主持国家自然科学基金青年项目1项(钌催化芳烃间位高位点选择性的C-H/Si-H脱氢偶联反应研究及应用,22101152,30万,在研)
(2)主持曲阜师范大学科研启动基金项目1项(614201,20万,在研)
(3)参与国家自然科学基金面上项目3项(22074079;21871151;21675099)
(4)指导山东省大学生创新创业项目1项(光催化构建苯并咪唑并噻唑类化合物的研究,S202010446090,已结题)
独立工作以来发表的第一通讯作者论文(至2023年11月):
(1)Kelu Yan,*,† Min Liu,† Jiangwei Wen, Shao Wang, Jing Li, and Hua Wang* Synthesis of Substituted Naphtho[1,8-bc]thiopyrans by Sulfhydryl-Directed Rhodium-Catalyzed peri-Selective C−H Bond Activation and Cyclization of Naphthalene-1-thiols. Org. Lett. 2020, 22, 7825−7830.
(2)Kelu Yan,*‡ Min Liu,‡ Jiangwei Wen, Xiao Liu, Xinyue Wang, Xinyu Chen, Jing Li, Shao Wang, Xiu Wang and Hua Wang* Visible-light-promoted cascade cyclization towards benzo[d]imidazo[5,1-b]thiazoles under metal- and photocatalyst-free conditions. Green Chem. 2021, 23, 1286–1291.
(3)Kelu Yan,*‡ Min Liu,‡ Jiangwei Wen, Weihua Liu, Xue Li, Xiao Liu, Xinlei Sui, Wenda Shang and Xiu Wang Copper-catalyzed domino synthesis of benzo[d]imidazo[5,1-b][1,3]selenazoles involving sequential intermolecular cycloaddition and intramolecular Ullmann-type C–Se bond formation. Org. Chem. Front. 2021, 8, 5139–5144.
(4)Min Liu,+ Kelu Yan,+,* Jiangwei Wen, Xue Li, Xiaoyu Wang, Fengjie Lu, Xiu Wang, and Hua Wang,* Synthesis of Polysubstituted Phenols by Rhodium-Catalyzed C–H/Diazo Coupling and Tandem Annulation. Adv. Synth. Catal. 2021, 363, 1855–1860.
(5)Min Liu,+ Kelu Yan,+,* Jiangwei Wen, Weihua Liu, Mingyu Wang, Lina Wang, and Xiu Wang Synthesis of Substituted 1-Hydroxy-2-Naphthaldehydes by Rhodium-Catalyzed C–H Bond Activation and Vinylene Transfer of Enaminones with Vinylene Carbonate. Adv. Synth. Catal. 2022, 364, 512–517.
(6)Min Liu,+ Kelu Yan,+,* Jiangwei Wen, Wenda Shang, Xinlei Sui, and Xiu Wang,* Ruthenium-Catalyzed C7-Formylmethylation or Sequential Acetalization of Indolines with Vinylene Carbonate in Different Solvents. Adv. Synth. Catal. 2022, 364, 1580– 1586.
(7)Kelu Yan,*‡ Min Liu,‡ Jiangwei Wen, Xiao Liu, Xiaoyu Wang, Xinlei Sui, Wenda Shang and Xiu Wang* Synthesis of 3-substituted quinolines by ruthenium-catalyzed aza-Michael addition and intramolecular annulations of enaminones with anthranils. New J. Chem. 2022, 46, 7329–7333.
(8)Kelu Yan*,1, Xiao Liu1, Min Liu, Jiangwei Wen, Mingyue Du, Yingxue Fu, Wenxin Chen Iridium-catalyzed oxidative coupling and cyclization of NH isoquinolones with olefins leading to isoindolo[2,1-b]isoquinolin-5(7H)-one derivatives. Tetrahedron Lett. 2022, 97, 153779.
(9)Min Liu+, Kelu Yan+,* Jiangwei Wen, Ning Zhang, Xinyu Chen, Xue Li, and Xiu Wang* PIFA Induced Regioselective C–H Chalcogenylation of Benzo[d]imidazo[5,1-b]thiazoles under Mild Conditions. Asian J. Org. Chem. 2022, 11, e202200381.
(10)Kelu Yan,* Xiaoyu Wang, Jiangwei Wen, Qiuyun Li, Ning Zhang, Shuyun Zhu, Xian-En Zhao, and Xiu Wang* Hydroxyl-Directed Iridium-Catalyzed Synthesis of Pyrano[2,3,4-de]chromen-2-ones and Further Chalcogenation under Blue-Light Irradiation. Eur. J. Org. Chem. 2022, e202201171.
(11)Min Liu+, Xinlei Sui+, Jiangwei Wen, Qiuyun Li, Xiao Liu, Xiaoyu Wang, Xiu Wang,* and Kelu Yan* Cobalt-Catalyzed Double C–H Activation of Imidazopyridines with Vinylene Carbonate for the Synthesis of Pyrido[1,2-a]benzimidazoles. Eur. J. Org. Chem. 2022, e202201349.
(12)Kelu Yan,* Xiao Liu, Jiangwei Wen, Qiuyun Li, Bingxin Zhou, Yuanyuan Zhang, and Xiu Wang* Synthesis of Substituted Pyrido[1,2-a]benzimidazoles by Ruthenium-Catalyzed C–H Bond Activation and Tandem Cyclization of 2-Arylimidazo[1,2-a]pyridines with Iodonium Ylides. Eur. J. Org. Chem. 2023, 26, e202300684.
(13)Xiaoyu Wang, Kelu Yan,* Jiangwei Wen, Qiuyun Li, Ke Ma, Wenlu Zhang, Wanhua Sun and Jianjing Yang* Synthesis of tetrasubstituted selenophenes by DBU-induced sequential three-component coupling and intramolecular cyclization. New J. Chem. 2023, 47, 19822–19826.
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